Hub 2: Improving outcomes for people at higher risk of cancer

The Daffodil Centre’s world-leading cancer control research includes risk-based approaches to prevention, screening and early detection as well as whole-of-population interventions. Research is focused on strengthening approaches to cancer control in people at higher risk of cancer.

Our researchers are working on:

Identifying women at increased risk of ovarian cancer and strategies for prevention and cancer control
Optimising detection and management of hereditary cancers, including cancers related to Lynch Syndrome
Understanding the role of direct-to-consumer genomic testing including, public perspectives and assessment of the benefits, harms, and health system demand
Tailoring melanoma screening and surveillance according to individual risk
Investigating the potential impact, cost-effectiveness and implementation of new strategies for lung cancer screening in high risk people in Australia and other high-income countries
Developing cancer risk prediction models for validation and evaluation.

Streams of work connected to this hub

Breast Cancer Clinical and Population Health

This stream of research encompasses clinical and population health studies and aims to provide new evidence to guide policy and practice in breast cancer screening, diagnosis, and prognostication.

Team info

Breast Cancer Policy and Evaluation

This stream of work is building evidence on the benefits, potential harms and costs of different approaches to optimise early detection and treatment of breast cancer and ultimately save more lives.

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Gastrointestinal Cancers Policy and Evaluation

This stream is developing a multi-stage program to address gastrointestinal cancer control challenges with a focus on the two highest burden cancers – colorectal and liver.

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Genomics and Precision Health

Integrating individual and population-level genomic, lifestyle, and medical information for successful precision health: tailoring the right intervention and support to the right population at the right time.

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Lung Cancer Policy and Evaluation

This stream is providing an evidence base for improving and sustaining tobacco control, optimising and implementing lung cancer screening, identifying effective and cost-effective lung cancer therapies, and ensuring equity in lung cancer care. 

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Mathematical Modelling

Mathematical modelling plays an increasingly important role in cancer control by helping to identify the most impactful and cost-effective ways to reduce the burden of cancer at a population level.

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Melanoma and Skin Cancer

This multidisciplinary research stream works across the skin cancer control continuum including aetiology, prevention, early detection, diagnosis, treatment and survivorship.

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Ovarian Cancer

Ovarian cancer has one of the lowest survival rates of any cancer in Australia and, unlike many other cancers, survival has only slightly improved in recent decades. This multidisciplinary stream of research is supported by key collaborators and advisors from across the Daffodil Centre, including experts in biology and translational research, epidemiology, mathematical modelling, implementation science, health economics, statistics and key stakeholders, including community partners and patient advocates.

Team info